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Can’t lose weight?

These are the markers that we would look at along with the functional ranges that are optimal!

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⚠ Disclaimer

These are the OPTIMAL ranges, not the normal ranges provided by places like labcorp/quest. The standard ranges are wider as they are looking at the median range for the whole population, which we know is diseased. So we want to look at OPTIMAL ranges rather than ‘normal’

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If these markers are off, your body is fighting an uphill battle when it comes to weight loss. Fixing insulin resistance, thyroid dysfunction, inflammation, and liver congestion is key to unlocking fat loss.

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💡 Fasting Insulin

This is one of the most important markers for weight loss resistance. High fasting insulin (above 8 uIU/mL) means your body is in fat-storage mode, not fat-burning mode. Ideally, you want it 4-6 for optimal metabolism.

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💡 HOMA-IR (Insulin Resistance Score)

This calculates insulin resistance using fasting insulin and glucose. A high score means your cells aren’t responding to insulin properly, making it harder to lose weight. Ideal range: Below 1.5.

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💡 Reverse T3 (rT3)

If this is high, it can block your active thyroid hormone (T3) from doing its job, slowing your metabolism. Stress, inflammation, and low-calorie diets can drive this up. Ideal range: 14.9-26.7 ng/dL.

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💡 Triglyceride-to-HDL Ratio

A high ratio (>2.5) suggests metabolic dysfunction and poor fat metabolism. Ideally, you want your triglycerides below 100 mg/dL and HDL in the range of 55-75 for males, and 65-85 for females mg/dL.

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💡 CRP (C-Reactive Protein, hsCRP)

Chronic inflammation can block weight loss and mess with insulin sensitivity. If your CRP is high (above 1.0 mg/L), your body is in an inflamed state, making fat loss harder.

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